Description

2-Fluoro-3-Methylsulfonylpyridine CAS NO 1254730-40-9 is a high-purity, functionalized pyridine derivative characterized by its unique fluorine and methylsulfonyl substituents. This compound serves as a critical building block in advanced organic synthesis, enabling the development of novel molecules with tailored properties. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Acts as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Cross-Coupling Reactions: Serves as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.

Basic Information

Product Name	2-Fluoro-3-Methylsulfonylpyridine
CAS No.	1254730-40-9
Molecular Formula	C6H6FNO2S
Molecular Weight	175.18 g/mol
Synonyms	2-Fluoro-3-(methylsulfonyl)pyridine; 3-Methylsulfonyl-2-fluoropyridine; Pyridine, 2-fluoro-3-(methylsulfonyl)-; 2-Fluoro-3-methanesulfonylpyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methylsulfonylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.