Description

4-(Benzyloxy)-2-Fluoropyridine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a benzyl-protected oxygen and a fluorine atom on the pyridine ring, makes it an invaluable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and functional polymers.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags or molecular probes for biochemical and diagnostic applications.
• Custom Synthesis and Scale-up: Supplied for contract research organizations (CROs) and CDMOs requiring high-quality, reliable intermediates for process development and commercial manufacturing.

Basic Information

Product Name	4-(Benzyloxy)-2-Fluoropyridine
CAS No.	1253792-64-1
Molecular Formula	C₁₂H₁₀FNO
Molecular Weight	203.21 g/mol
Synonyms	2-Fluoro-4-(phenylmethoxy)pyridine; 4-Benzyloxy-2-fluoropyridine; 2-Fluoro-4-(benzyloxy)pyridine; Pyridine, 2-fluoro-4-(phenylmethoxy)-; 4-(Benzyloxy)-2-fluoro-pyridine; 2-Fluor-4-benzyloxypyridin
EINECS	Contact for details

Quality Control

Every batch of 4-(Benzyloxy)-2-Fluoropyridine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation (by NMR and IR), and levels of specific impurities. Our quality commitment supports applications in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.