Description

4-(Trifluoromethyl)Thiazole-2-Carboximidamide Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl-thiazole core. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in antiviral, anticancer, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Serves as a precursor in the synthesis of novel pesticides and herbicides, leveraging the biological activity of the thiazole ring.
• Chemical Biology Probe: Used in biochemical research to study enzyme interactions and cellular pathways due to its specific molecular recognition properties.
• Material Science: Potential building block for advanced functional materials, such as liquid crystals or organic semiconductors, where fluorine substitution is advantageous.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	4-(Trifluoromethyl)Thiazole-2-Carboximidamide Hydrochloride
CAS No.	1251166-15-0
Molecular Formula	C5H5F3N3S·HCl
Molecular Weight	235.63 g/mol (Free base: 199.17 g/mol)
Synonyms	2-Carbamimidoyl-4-(trifluoromethyl)-1,3-thiazole Hydrochloride; 4-(Trifluoromethyl)-2-thiazolecarboximidamide Hydrochloride; 4-(Trifluoromethyl)thiazole-2-carboximidamide HCl; 2-Thiazolecarboximidamide, 4-(trifluoromethyl)-, hydrochloride; 1251166-15-0; 4-Trifluoromethylthiazole-2-carboximidamide hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Thiazole-2-Carboximidamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.