Description

Difluoro-Pyrimidin-5-Yl-Acetic Acid Ethyl Ester is a high-purity fluorinated pyrimidine derivative, a crucial building block in modern synthetic chemistry. Its value lies in its unique molecular structure, which serves as a versatile synthon for constructing complex heterocyclic compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the difluoropyrimidine core.
• Material Science: Serves as a precursor for advanced materials, including liquid crystals and organic semiconductors.
• Chemical Synthesis: A versatile reagent in organic synthesis for introducing the difluoropyrimidinyl-acetate moiety into more complex molecular architectures.
• Life Sciences & Diagnostics: Employed in the development of molecular probes, fluorescent tags, and other diagnostic tools.

Basic Information

Product Name	Difluoro-Pyrimidin-5-Yl-Acetic Acid Ethyl Ester
CAS No.	1250685-30-3
Molecular Formula	C9H8F2N2O2
Molecular Weight	214.17 g/mol
Synonyms	Ethyl 2-(2,4-difluoropyrimidin-5-yl)acetate; 5-(Ethoxycarbonylmethyl)-2,4-difluoropyrimidine; 2,4-Difluoropyrimidine-5-acetic acid ethyl ester; 2-(2,4-Difluoropyrimidin-5-yl)acetic acid ethyl ester; Difluoropyrimidinyl Acetic Acid Ethyl Ester; 1250685-30-3; 5-Acetic acid, ethyl ester, 2,4-difluoropyrimidine
EINECS	Contact for details

Quality Control

Our Difluoro-Pyrimidin-5-Yl-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.