Description

4-Piperidinecarboxylic Acid, 4-Fluoro-1-(Phenylmethyl)-, Ethyl Ester is a high-value, fluorinated piperidine derivative that serves as a critical building block in modern synthetic chemistry. This compound is engineered to introduce both a fluorinated piperidine scaffold and a benzyl-protected amine, making it indispensable for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated piperidine core, which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced pesticides and herbicides that require specific fluorinated heterocyclic structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and fluorine chemistry.

Basic Information

Product Name	4-Piperidinecarboxylic Acid, 4-Fluoro-1-(Phenylmethyl)-, Ethyl Ester
CAS No.	1250443-08-3
Molecular Formula	C15H20FNO2
Molecular Weight	265.33 g/mol
Synonyms	Ethyl 4-Fluoro-1-benzylpiperidine-4-carboxylate; 1-Benzyl-4-fluoro-4-piperidinecarboxylic Acid Ethyl Ester; 4-Fluoro-1-benzylpiperidine-4-carboxylic Acid Ethyl Ester; 4-Fluoro-1-(phenylmethyl)piperidine-4-carboxylic Acid Ethyl Ester; 1-Benzyl-4-fluoropiperidine-4-carboxylic Acid Ethyl Ester; 4-Fluoro-1-benzyl-4-piperidinecarboxylic Acid Ethyl Ester; 4-Fluoro-1-(benzyl)piperidine-4-carboxylate Ethyl Ester
EINECS	Contact for details

Quality Control

Our 4-Piperidinecarboxylic Acid, 4-Fluoro-1-(Phenylmethyl)-, Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.