Description

3-Bromo-2-(Difluoromethoxy)Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block designed for advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines bromine and difluoromethoxy substituents to enable precise chemical modifications and introduce desirable properties into target molecules. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Advanced Material Precursor: Employed in the synthesis of organic electronic materials, liquid crystals, and specialty polymers where halogen and fluorine atoms tune electronic and physical properties.
• Chemical Research & Development: A versatile reagent for exploring new reaction pathways, such as Suzuki-Miyaura couplings or nucleophilic aromatic substitutions, in academic and industrial R&D laboratories.

Basic Information

Item	Detail
Product Name	3-Bromo-2-(Difluoromethoxy)Benzaldehyde
CAS No.	1249999-12-9
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	2-(Difluoromethoxy)-3-bromobenzaldehyde; 3-Bromo-2-difluoromethoxybenzaldehyde; Benzaldehyde, 3-bromo-2-(difluoromethoxy)-; 1249999-12-9; 3-Bromo-2-(difluoromethoxy)benzaldehyde; 2-(Difluoromethoxy)-3-bromo-benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-(Difluoromethoxy)Benzaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); therefore, it is recommended to handle and store under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.