Description

1-Methyl-3-Phenyl-1H-Pyrazole-5-Sulfonyl Chloride is a high-value sulfonyl chloride derivative used as a key synthetic intermediate in advanced organic chemistry. This compound is critical for introducing the sulfonyl functional group, enabling the construction of complex molecules with tailored properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of new-generation herbicides, fungicides, and insecticides, where the sulfonyl moiety imparts specific biological activity.
• Material Science Research: Serves as a precursor for creating functional polymers, dyes, and advanced organic materials with specific electronic or photophysical properties.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes (ABPs) and other molecular tools for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	1-Methyl-3-Phenyl-1H-Pyrazole-5-Sulfonyl Chloride
CAS No.	1249907-52-5
Molecular Formula	C10H9ClN2O2S
Molecular Weight	256.71 g/mol
Synonyms	1-Methyl-3-phenyl-1H-pyrazole-5-sulfonyl chloride; 3-Phenyl-1-methyl-1H-pyrazole-5-sulfonyl chloride; 1-Methyl-3-phenylpyrazole-5-sulfonyl chloride; 5-(Chlorosulfonyl)-1-methyl-3-phenyl-1H-pyrazole; Pyrazole-5-sulfonyl chloride, 1-methyl-3-phenyl-
EINECS	Contact for details

Quality Control

Every batch of 1-Methyl-3-Phenyl-1H-Pyrazole-5-Sulfonyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.