Description

3-Cyanopyridine-2-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2-sulfonyl functional group into heterocyclic systems, facilitating the development of novel compounds with targeted properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially sulfonamide-based therapeutics targeting various enzymes and receptors.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyridine-sulfonyl moiety imparts specific biological activity.
• Functional Material Research: Serves as a monomer or cross-linking agent in the creation of specialty polymers, coatings, and advanced materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of activity-based probes to study enzyme function.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Cyanopyridine-2-Sulfonyl Chloride
CAS No.	1249854-80-5
Molecular Formula	C6H3ClN2O2S
Molecular Weight	202.62 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 3-cyano-; 3-Cyano-2-pyridinesulfonyl chloride; 3-Cyanopyridine-2-sulfonyl chloride; 2-Chlorosulfonyl-3-cyanopyridine; 3-Cyano-2-pyridylsulfonyl chloride; 3-Cyanopyridine-2-sulfonchlorid; 3-CN-Pyridine-2-SO2Cl
EINECS	Contact for details

Quality Control

Every batch of 3-Cyanopyridine-2-Sulfonyl Chloride is manufactured and tested under a strict quality management system. We ensure compliance with rigorous internal specifications, which are designed to meet the demanding requirements of research and commercial synthesis. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.