Description

2-Isopropoxy-Ethanesulfonyl Chloride is a specialized organosulfur reagent primarily used as a key sulfonylation building block in advanced organic synthesis. This compound matters for its role in introducing the 2-isopropoxyethanesulfonyl functional group, a moiety of interest in medicinal chemistry and materials science. Industries that need it include pharmaceutical R&D for creating novel active pharmaceutical ingredients (APIs) and agrochemical manufacturers developing new crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel sulfonamide-based drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides with sulfonyl-containing active ingredients.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with sulfone linkages for enhanced thermal and chemical resistance.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Ligand and Catalyst Development: Useful for modifying ligands in transition metal catalysis to fine-tune electronic and steric properties.
• Material Science Research: Applied in the surface functionalization of materials to introduce specific sulfonyl groups for desired interfacial properties.

Basic Information

Product Name	2-Isopropoxy-Ethanesulfonyl Chloride
CAS No.	1249441-42-6
Molecular Formula	C5H11ClO3S
Molecular Weight	186.66 g/mol
Synonyms	2-Isopropoxyethanesulfonyl chloride; 2-(Isopropoxy)ethanesulfonyl chloride; 1-Isopropoxy-2-chlorosulfonylethane; Ethanesulfonyl chloride, 2-isopropoxy-; Isopropoxyethylsulfonyl chloride; 2-(Propan-2-yloxy)ethane-1-sulfonyl chloride; (2-Isopropoxyethyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Isopropoxy-Ethanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.