Description

(4-Fluoro-2-Methylphenyl)Methanesulfonyl Chloride CAS NO 1248508-79-3 is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its high reactivity as a sulfonylation reagent, enabling the efficient introduction of the (4-fluoro-2-methylphenyl)methanesulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where precise structural modification is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine and sulfonyl groups for enhanced bioactivity and environmental stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the creation of specialty polymers and advanced materials with specific surface properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling, modifying, or inhibiting biological targets in probe and drug discovery efforts.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	(4-Fluoro-2-Methylphenyl)Methanesulfonyl Chloride
CAS No.	1248508-79-3
Molecular Formula	C9H8ClFO2S
Molecular Weight	234.67 g/mol
Synonyms	4-Fluoro-2-methylbenzenemethanesulfonyl chloride; 1-(Chlorosulfonyl)methyl-4-fluoro-2-methylbenzene; (4-Fluoro-o-tolyl)methanesulfonyl chloride; 2-Methyl-4-fluorobenzylsulfonyl chloride; α-Chlorosulfonyl-4-fluoro-2-methyltoluene; 4-Fluoro-2-methylbenzylsulfonyl chloride; (4-Fluoro-2-methylbenzyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of (4-Fluoro-2-Methylphenyl)Methanesulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot undergoes comprehensive analysis, including purity assay and impurity profiling via advanced chromatographic techniques. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.