Description

1-(2,4-Difluorophenyl)Ethane-1-Sulfonyl Chloride is a specialized organosulfur compound featuring a sulfonyl chloride functional group attached to a difluorinated phenyl ring. This molecular architecture makes it a versatile and critical building block in advanced organic synthesis, particularly for the introduction of sulfonamide moieties. It is primarily sought after by pharmaceutical and agrochemical research & development teams for creating novel active ingredients and intermediates. The compound's reactivity is essential for developing products with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing sulfonamide-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that utilize sulfonamide chemistry.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology & Proteomics: Employed as a reactive probe or labeling reagent for studying protein interactions and enzyme activity.
• Custom Synthesis & Contract Manufacturing: A crucial reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	1-(2,4-Difluorophenyl)Ethane-1-Sulfonyl Chloride
CAS No.	1248002-37-0
Molecular Formula	C8H7ClF2O2S
Molecular Weight	240.65 g/mol
Synonyms	1-(2,4-Difluorophenyl)ethanesulfonyl chloride; 2,4-Difluorophenyl Ethyl Sulfonyl Chloride; α-(2,4-Difluorophenyl)ethanesulfonyl Chloride; 1-(2,4-Difluorophenyl)-1-ethanesulfonyl Chloride; 2,4-DFPESC; (2,4-Difluorophenyl)methylsulfonyl Chloride (common misnomer); Ethanesulfonyl chloride, 1-(2,4-difluorophenyl)-; 1248002-37-0
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorophenyl)Ethane-1-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.