Description

5-Fluoropyridine-3-Sulfonamide is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a fluorine atom and a sulfonamide group on the pyridine scaffold, enabling precise modulation of molecular properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and enzyme modulator programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine and sulfonamide groups contribute to bioactivity and environmental stability.
• Chemical Biology Probe: Serves as a versatile scaffold for designing molecular probes to study protein-ligand interactions and biological pathways.
• Material Science Research: Employed in the synthesis of functionalized ligands for catalysts or as a precursor for specialty polymers and advanced materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated pyridine derivatives.

Basic Information

Product Name	5-Fluoropyridine-3-Sulfonamide
CAS No.	1247591-65-6
Molecular Formula	C5H5FN2O2S
Molecular Weight	176.17 g/mol
Synonyms	3-Sulfamoyl-5-fluoropyridine; 5-Fluoro-3-pyridinesulfonamide; 5-Fluoropyridine-3-sulfonic acid amide; 5-Fluoro-3-sulfamoylpyridine; 1247591-65-6; 5-Fluoropyridin-3-ylsulfonamide
EINECS	Contact for details

Quality Control

Our 5-Fluoropyridine-3-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.