Description

6-(2,2,2-Trifluoroethoxy)Pyridine-2-Carboxylic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluoroethoxy side chain, is engineered to impart unique electronic and steric properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and liquid crystals for electronic and optical applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	6-(2,2,2-Trifluoroethoxy)Pyridine-2-Carboxylic Acid
CAS No.	1247503-48-5
Molecular Formula	C8H6F3NO3
Molecular Weight	221.13 g/mol
Synonyms	2-Pyridinecarboxylic acid, 6-(2,2,2-trifluoroethoxy)-; 6-(Trifluoroethoxy)picolinic acid; 6-(2,2,2-Trifluoroethoxy)-2-pyridinecarboxylic acid; 6-(Trifluoroethoxy)pyridine-2-carboxylic acid; 2-Carboxy-6-(2,2,2-trifluoroethoxy)pyridine; Picolinic acid, 6-(trifluoroethoxy)-
EINECS	Contact for details

Quality Control

Our production of 6-(2,2,2-Trifluoroethoxy)Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch is analytically verified to meet exacting purity standards, with comprehensive testing including HPLC for assay and related substances. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.