Description

1H-Pyrazole-4-Sulfonyl Chloride, 1-(4-Methyl-2-Pyridinyl)- is a high-purity, heterocyclic sulfonyl chloride derivative of significant interest in advanced organic synthesis. Its core value lies in its role as a versatile and reactive sulfonylation reagent, enabling the efficient introduction of a functionalized pyrazole-sulfonyl moiety into target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the sulfonamide linkage is a common pharmacophore.
• Chemical Biology Probe Synthesis: Employed to create sulfonamide-based probes for studying protein function and biological pathways.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialized polymers and advanced materials.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new reactions involving sulfonyl chlorides.

Basic Information

Product Name	1H-Pyrazole-4-Sulfonyl Chloride, 1-(4-Methyl-2-Pyridinyl)-
CAS No.	1247076-12-5
Molecular Formula	C9H8ClN3O2S
Molecular Weight	257.70 g/mol
Synonyms	1-(4-Methylpyridin-2-yl)-1H-pyrazole-4-sulfonyl chloride; 1-(4-Methyl-2-pyridinyl)-1H-pyrazole-4-sulfonyl chloride; 4-Methyl-2-(4-(sulfonyl chloride)-1H-pyrazol-1-yl)pyridine; 1-(4-Methyl-2-pyridyl)pyrazole-4-sulfonyl chloride; 1-(4-Methylpyrid-2-yl)pyrazole-4-sulfonyl chloride; 1-(4-Methyl-2-pyridinyl)-1H-pyrazole-4-sulfonylchloride; 1-(4-Methyl-2-pyridyl)-1H-pyrazole-4-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-4-Sulfonyl Chloride, 1-(4-Methyl-2-Pyridinyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.