Description

(S)-Carisbamate-13C,15N,D2 is a stable isotope-labeled analog of the investigational anticonvulsant agent Carisbamate. This compound is specifically designed for use as an internal standard in quantitative bioanalytical methods, providing unmatched accuracy and reliability in pharmacokinetic and metabolism studies. It is an essential tool for pharmaceutical R&D, contract research organizations (CROs), and analytical laboratories focused on advancing neurological therapeutics.

Application

• Bioanalytical Internal Standard: Primary use as a stable isotope-labeled internal standard for the precise quantification of Carisbamate and its metabolites in biological matrices (plasma, serum, urine) via LC-MS/MS.
• Pharmacokinetic (PK) Studies: Enables accurate determination of absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical and clinical research.
• Drug Metabolism Studies: Facilitates the identification and quantification of metabolite formation, crucial for understanding drug safety and efficacy.
• Method Development & Validation: Serves as a critical component in developing and validating robust, GLP-compliant analytical methods for regulatory submissions.
• Doping Control & Forensic Analysis: Potential application in specialized testing protocols requiring high-specificity detection of Carisbamate.

Basic Information

Product Name	(S)-Carisbamate-13C,15N,D2
CAS No.	1246817-83-3
Molecular Formula	C10H10D213C15NO4
Molecular Weight	Contact for details
Synonyms	(S)-2-Hydroxy-2-(2-chlorophenyl)ethyl carbamate-13C,15N,D2
(S)-RWJ-333369-13C,15N,D2
Carisbamate (S-isomer)-13C,15N,D2
Carisbamate-d2-13C,15N
Stable Isotope Labeled (S)-Carisbamate
Deuterated and 13C,15N-Labeled Carisbamate
Internal Standard for Carisbamate LC-MS
EINECS	Contact for details

Quality Control

Every batch of (S)-Carisbamate-13C,15N,D2 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity to ensure optimal performance as an internal standard. Comprehensive characterization includes NMR (1H, 13C), mass spectrometry, and chiral purity verification. A detailed Certificate of Analysis (COA) providing batch-specific data on purity, isotopic enrichment, and solvent content is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 99 atom % 15N; ≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.