Description

1-(3,4-Dimethylphenyl)Ethanol-13C,D3 is a stable isotope-labeled analog of 1-(3,4-dimethylphenyl)ethanol, where specific carbon and hydrogen atoms are replaced with 13C and deuterium (D), respectively. This compound is of critical importance as an internal standard in quantitative mass spectrometry, enabling precise and accurate measurement of its unlabeled counterpart in complex matrices. It is primarily needed by analytical laboratories, pharmaceutical R&D teams, and contract research organizations (CROs) engaged in method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS: Essential for the accurate quantification of 1-(3,4-dimethylphenyl)ethanol and related metabolites in biological samples (plasma, urine, tissue).
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to track absorption, distribution, metabolism, and excretion (ADME) profiles.
• Biomarker Analysis: Facilitates the precise measurement of endogenous or exogenous compounds in clinical and forensic toxicology.
• Method Development & Validation: Serves as a critical tool for developing and validating robust, regulatory-compliant analytical methods (e.g., following FDA/EMA guidelines).
• Environmental & Food Safety Testing: Potential use in trace analysis of related phenolic compounds in environmental or agricultural samples.
• Isotope Dilution Mass Spectrometry (IDMS): Employed in high-precision analytical techniques that require the highest level of accuracy and minimal matrix effects.

Basic Information

Product Name	1-(3,4-Dimethylphenyl)Ethanol-13C,D3
CAS No.	1246816-91-0
Molecular Formula	C9H10D3O (with one 13C atom)
Molecular Weight	~151.22 g/mol (isotopic average)
Synonyms	1-(3,4-Dimethylphenyl)Ethanol-1-13C,d3; 1-(3,4-Xylyl)Ethanol-13C,D3; (3,4-Dimethylphenyl)(1-13C,d3)Methanol; 1-(3,4-Dimethylphenyl)(1-13C,d3)Ethanol; 2-(3,4-Dimethylphenyl)Ethanol-1-13C,d3 (if numbered differently); 3,4-Dimethylbenzeneethanol-13C,D3; Isotopically Labeled 1-(3,4-DMP)Ethanol; 13C Deuterated 1-(3,4-Dimethylphenyl)Ethanol
EINECS	Contact for details

Quality Control

Our stable isotope-labeled products are manufactured under strict quality systems to ensure high isotopic purity and chemical purity. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and high-resolution mass spectrometry to confirm isotopic enrichment and identity. Certificates of Analysis (COA) are provided, detailing isotopic purity (atom % 13C and D), chemical purity, and solvent content. We support compliance with cGMP and ISO 9001 standards for research and regulatory applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container sealed in a dry and well-ventilated place. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (13C)	≥ 99 atom %
Isotopic Purity (D)	≥ 98 atom % (D3)
Chemical Purity (GC/HPLC)	≥ 95.0%
Solvent Content (Residual Solvents)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.