Description

4-n-(7-Chloroquinolin-4-Yl)-1,1,2,2-Tetradeuterio-1-N,1-n-Diethylpentane-1,4-Diamine CAS NO 1246815-14-4 is a deuterated derivative of a quinoline-based diamine compound, serving as a critical stable isotope-labeled intermediate. Its primary value lies in enabling advanced research and development within pharmaceutical and agrochemical sectors, particularly for metabolic studies, pharmacokinetics, and the synthesis of novel active ingredients. This high-purity compound is essential for scientists and manufacturers requiring precise, reliable building blocks for deuterium-labeled molecules.

Application

• Pharmaceutical Research & Development: As a stable isotope-labeled intermediate for the synthesis of deuterated drug candidates, enhancing metabolic stability and enabling detailed ADME (Absorption, Distribution, Metabolism, Excretion) studies.
• Metabolic Pathway Tracing: Utilization in mass spectrometry and NMR-based assays to track and quantify metabolic products in biological systems.
• Agrochemical Innovation: Intermediate for developing novel, deuterated active ingredients aimed at improving efficacy and environmental profiles of crop protection agents.
• Chemical Biology Probes: Synthesis of specialized molecular probes for investigating biological mechanisms and target engagement.
• Reference Standard Production: Serves as a key starting material for manufacturing certified reference standards used in analytical method development and validation.
• Isotope Effect Studies: Fundamental research tool for studying kinetic isotope effects (KIE) in chemical and enzymatic reactions.

Basic Information

Item	Details
Product Name	4-n-(7-Chloroquinolin-4-Yl)-1,1,2,2-Tetradeuterio-1-N,1-n-Diethylpentane-1,4-Diamine
CAS No.	1246815-14-4
Molecular Formula	C18H22D4ClN3
Molecular Weight	319.89 g/mol (approx.)
Synonyms	1,1,2,2-Tetradeuterio-N1,N1-diethyl-N4-(7-chloroquinolin-4-yl)pentane-1,4-diamine; 7-Chloro-4-[[4-(diethylamino)-1,1,2,2-tetradeuterio-1-methylbutyl]amino]quinoline-d4; Deuterated Chloroquine Analog Intermediate; 4-[(4-Diethylamino-1,1,2,2-tetradeuterio-1-methylbutyl)amino]-7-chloroquinoline; N1,N1-Diethyl-N4-(7-chloro-4-quinolyl)-1,1,2,2-tetradeuterio-1-methylbutane-1,4-diamine; 1,1,2,2-Tetradeuterio-1-N,1-n-diethyl-4-n-(7-chloroquinolin-4-yl)pentane-1,4-diamine
EINECS	Contact for details

Quality Control

Our 4-n-(7-Chloroquinolin-4-Yl)-1,1,2,2-Tetradeuterio-1-N,1-n-Diethylpentane-1,4-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and isotopic enrichment, NMR for structural confirmation, and mass spectrometry to ensure compliance with exacting specifications for research and development use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Enrichment (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.