Description

4-[(4,6-Dihydroxy-2-Pyrimidinyl)Amino]Benzonitrile-13C3 is a stable isotope-labeled analog of a pyrimidine derivative, where three carbon atoms are replaced with the carbon-13 isotope. This compound is a critical tool for quantitative analysis and metabolic pathway tracing in advanced pharmaceutical and biochemical research. It is primarily utilized by researchers and developers in the fields of drug discovery, pharmacokinetics, and analytical method development requiring high-purity, isotopically labeled internal standards.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification in bioanalytical studies.
• Tracer compound for investigating drug metabolism and pharmacokinetic profiles.
• Critical reagent in the development and validation of high-sensitivity analytical methods for active pharmaceutical ingredients (APIs).
• Use in proteomics and metabolomics research for precise mass spectrometry-based measurements.
• Chemical reference material for quality control laboratories in pharmaceutical manufacturing.
• Substrate for enzymatic and binding studies requiring isotopically labeled ligands.

Basic Information

Product Name	4-[(4,6-Dihydroxy-2-Pyrimidinyl)Amino]Benzonitrile-13C3
CAS No.	1246814-95-8
Molecular Formula	C713C3H8N4O2
Molecular Weight	~221.17 g/mol (for 13C3 labeled form)
Synonyms	4-[(4,6-Dihydroxy-2-pyrimidinyl)amino]benzonitrile-13C3; 2-Amino-4,6-dihydroxypyrimidine-5-benzonitrile-13C3; Benzonitrile-13C3, 4-[(4,6-dihydroxy-2-pyrimidinyl)amino]-; 13C3-Labeled 4-(4,6-Dihydroxy-2-pyrimidinylamino)benzonitrile; Isotopically labeled pyrimidine derivative; 13C3-4-DHAPB; [13C3]-4-[(4,6-Dihydroxy-2-pyrimidinyl)amino]benzonitrile
EINECS	Contact for details

Quality Control

Every batch of our 4-[(4,6-Dihydroxy-2-Pyrimidinyl)Amino]Benzonitrile-13C3 is manufactured and tested under strict quality systems to ensure exceptional isotopic and chemical purity for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical method data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, consider storage under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C
Isotopic Purity (13C3)	≥ 98%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.