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10-Benzyloxyethoxyphosphinyl-n-Biotinamidopentyldecanamide CAS NO 1246814-51-6
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CAS No.:1246814-51-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
10-Benzyloxyethoxyphosphinyl-n-Biotinamidopentyldecanamide is a sophisticated, high-purity biochemical building block designed for advanced research and development. This compound is critical for scientists working on targeted drug delivery systems and bioconjugation strategies, particularly in the fields of oncology and diagnostics. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on creating novel biotinylated probes and conjugates.
Application
- Bioconjugation Reagent: Used for the site-specific labeling of proteins, antibodies, and other biomolecules with biotin for detection and purification.
- Drug Delivery System Development: Serves as a key intermediate in the synthesis of targeted prodrugs and antibody-drug conjugates (ADCs).
- Diagnostic Probe Synthesis: Essential for creating high-affinity biotinylated probes used in ELISA, immunohistochemistry, and flow cytometry.
- Chemical Biology Research: Enables the study of protein-protein interactions and cellular pathways through biotin-streptavidin technology.
- Pharmaceutical Intermediate: A critical precursor in the synthesis of novel therapeutic agents requiring biotin-mediated targeting.
- Affinity Chromatography Ligand: Can be immobilized to create resins for the purification of specific biomolecules.
Basic Information
| Product Name | 10-Benzyloxyethoxyphosphinyl-n-Biotinamidopentyldecanamide |
| CAS No. | 1246814-51-6 |
| Molecular Formula | C33H54N4O7PS |
| Molecular Weight | 681.84 g/mol |
| Synonyms | Biotin-PEG2-Benzyl Phosphoramidate; 5-((6-((5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl)amino)-5-oxopentyl) 2-(benzyloxy)ethyl hydrogen phosphonate; Biotinamidopentyl-PEG2-Benzyl Phosphoramidate; Biotinylated Benzyl Phosphoramidate Linker; N-Biotinoyl-1,6-diaminohexane PEG2-Benzyl Phosphoramidate |
| EINECS | Contact for details |
Quality Control
Our 10-Benzyloxyethoxyphosphinyl-n-Biotinamidopentyldecanamide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support its use in pharmaceutical development.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Solubility | Soluble in DMSO, DMF; Slightly soluble in methanol |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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