Description

D-Erythro-Sphinganine-D7 is a high-purity, deuterium-labeled internal standard critical for advanced analytical research. This compound is essential for ensuring the accuracy and precision of quantitative mass spectrometry analyses in lipidomics and metabolic studies. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors who require reliable standards for sphingolipid pathway analysis.

Application

• Used as a deuterated internal standard for the precise quantification of sphinganine and related sphingolipids via LC-MS/MS and GC-MS.
• Critical in lipidomics research for studying sphingolipid metabolism, cell signaling, and biomarker discovery.
• Facilitates drug metabolism and pharmacokinetic (DMPK) studies for pharmaceutical compounds targeting lipid pathways.
• Supports clinical diagnostics development for diseases associated with sphingolipid imbalances.
• Enables high-throughput screening in biochemical assays to identify modulators of enzymes like serine palmitoyltransferase.
• Applied in toxicology studies to assess the impact of mycotoxins (like fumonisins) and other agents on sphingolipid biosynthesis.

Basic Information

Product Name	D-Erythro-Sphinganine-D7
CAS No.	1246304-35-7
Molecular Formula	C18D7H31NO2
Molecular Weight	304.5 g/mol (approx.)
Synonyms	(2S,3R)-2-Amino-1,3-octadecanediol-D7; D-erythro-Dihydrosphingosine-D7; D-erythro-Sphinganine (2,3,4,5,6,7,7-D7); (2S,3R)-2-Amino-1,3-octadecanediol-2,3,4,5,6,7,7-d7; Deuterated Sphinganine; D-erythro-C18-Sphinganine-D7; Dihydro-D-erythro-sphingosine-D7; Sa(d18:0)-D7
EINECS	Contact for details

Quality Control

Every batch of D-Erythro-Sphinganine-D7 is manufactured and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive characterization by NMR, MS, and HPLC. A Certificate of Analysis (COA) detailing purity, isotopic enrichment, and analytical data is provided with each shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and moisture absorption. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.