Description

(5-Fluoro-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Methanol is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, especially for projects targeting kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for novel therapeutic candidates.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation fluorinated agrochemicals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Organic Electronic Materials: Potential precursor for developing fluorinated heterocyclic compounds used in organic semiconductors.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	(5-Fluoro-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Methanol
CAS No.	1246088-53-8
Molecular Formula	C8H7FN2O
Molecular Weight	166.15 g/mol
Synonyms	4-(Hydroxymethyl)-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-4-(hydroxymethyl)-1H-pyrrolo[2,3-b]pyridine; (5-Fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)methanol; 1H-Pyrrolo[2,3-b]pyridine-4-methanol, 5-fluoro-; 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-methanol
EINECS	Contact for details

Quality Control

Our (5-Fluoro-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and MS. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.