Description

5-Isopropylthiophene-3-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 5-isopropylthiophene-3-sulfonyl moiety, a key functional group for modulating the physicochemical properties of target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of sulfonamide-based drugs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the thiophene-sulfonyl group contributes to biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced functional materials.
• Chemical Research: A versatile reagent in organic chemistry for constructing complex molecular architectures in medicinal chemistry and process development.
• Dye & Pigment Industry: Intermediate in the synthesis of specialized dyes and pigments containing heterocyclic sulfone components.

Basic Information

Product Name	5-Isopropylthiophene-3-Sulfonyl Chloride
CAS No.	1245823-84-0
Molecular Formula	C7H9ClO2S2
Molecular Weight	224.73 g/mol
Synonyms	3-Isopropylthiophene-5-sulfonyl chloride; 5-(Propan-2-yl)thiophene-3-sulfonyl chloride; 3-Thiophenesulfonyl chloride, 5-(1-methylethyl)-; 5-(1-Methylethyl)-3-thiophenesulfonyl chloride; Isopropylthiophenesulfonyl Chloride; 5-Isopropyl-3-thiophenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Isopropylthiophene-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.