Description

2,2-Difluoro-1-(1-Isobutyl-1H-Pyrazol-4-Yl)Ethanone is a high-purity fluorinated pyrazole derivative, a key building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a difluoroacetyl moiety and a protected pyrazole ring, enabling precise modifications in complex chemical pathways. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Serves as a versatile scaffold for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the research and development of advanced polymers and liquid crystals, where the fluorine atoms impart desirable thermal and chemical stability.
• Organic Synthesis Building Block: Enables the introduction of the difluoroacetyl group into complex molecules, facilitating structure-activity relationship (SAR) studies in medicinal chemistry.
• Fluorine Chemistry Research: An important reagent for academic and industrial research focused on exploring new fluorination reactions and the properties of fluorinated heterocycles.

Basic Information

Product Name	2,2-Difluoro-1-(1-Isobutyl-1H-Pyrazol-4-Yl)Ethanone
CAS No.	1245823-42-0
Molecular Formula	C9H12F2N2O
Molecular Weight	202.20 g/mol
Synonyms	1-(1-Isobutyl-1H-pyrazol-4-yl)-2,2-difluoroethanone; 2,2-Difluoro-1-(1-isobutyl-1H-pyrazol-4-yl)ethan-1-one; 2,2-Difluoro-1-(1-isobutylpyrazol-4-yl)ethanone; 1245823-42-0; 1-(1-(2-Methylpropyl)-1H-pyrazol-4-yl)-2,2-difluoroethanone; 2,2-Difluoro-1-(1-isobutyl-1H-1,2,3-pyrazol-4-yl)ethanone; Difluoro(1-isobutyl-1H-pyrazol-4-yl)methanone
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-1-(1-Isobutyl-1H-Pyrazol-4-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.