Description

4-Chloro-1-Ethyl-1H-Pyrazole-5-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate essential for advanced synthesis. Its core value lies in its dual reactive sites, making it a versatile building block for constructing complex heterocyclic and sulfonamide-based molecules. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-containing drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with sulfonyl chloride moieties for enhanced activity.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced organic materials requiring specific pyrazole-based architectures.
• Chemical Biology Probes: Employed in the creation of activity-based probes and covalent inhibitors for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functionalization on the pyrazole ring system.

Basic Information

Product Name	4-Chloro-1-Ethyl-1H-Pyrazole-5-Sulfonyl Chloride
CAS No.	1245822-74-5
Molecular Formula	C5H6Cl2N2O2S
Molecular Weight	229.08 g/mol
Synonyms	1-Ethyl-4-chloro-1H-pyrazole-5-sulfonyl chloride; 4-Chloro-1-ethylpyrazole-5-sulfonyl chloride; 1H-Pyrazole-5-sulfonyl chloride, 4-chloro-1-ethyl-; 4-Chloro-1-ethyl-1H-pyrazole-5-sulfonylchloride; 1245822-74-5; 4-Chloro-1-ethylpyrazole-5-sulphonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-1-Ethyl-1H-Pyrazole-5-Sulfonyl Chloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.