Description

1-Isobutyl-3-Methyl-1H-Pyrazole-5-Sulfonyl Chloride is a high-value sulfonyl chloride derivative used as a key synthetic intermediate in advanced organic chemistry. Its primary commercial value lies in its role as a versatile electrophile for introducing the sulfonamide functional group, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the sulfonamide moiety can enhance efficacy and environmental profile.
• Chemical Biology & Proteomics: Serves as a reagent for chemical probe development and activity-based protein profiling (ABPP) to study enzyme function and identify drug targets.
• Material Science Research: Employed in the synthesis of functional polymers and advanced materials where sulfonamide linkages can impart specific thermal or chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	1-Isobutyl-3-Methyl-1H-Pyrazole-5-Sulfonyl Chloride
CAS No.	1245806-70-5
Molecular Formula	C9H15ClN2O2S
Molecular Weight	250.75 g/mol
Synonyms	1-Isobutyl-3-methyl-1H-pyrazole-5-sulfonyl chloride; 3-Methyl-1-isobutyl-1H-pyrazole-5-sulfonyl chloride; 1H-Pyrazole-5-sulfonyl chloride, 1-isobutyl-3-methyl-; Pyrazole sulfonyl chloride derivative; Isobutyl methyl pyrazole sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Isobutyl-3-Methyl-1H-Pyrazole-5-Sulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.