Description

2-Fluoro-6-m-Tolylpyridine is a high-value fluorinated pyridine derivative, a key building block in advanced organic synthesis. This compound is prized for its role in modulating the physicochemical properties of target molecules, particularly in pharmaceutical research and development. It serves as a critical intermediate for medicinal chemists and agrochemical researchers seeking to introduce fluorine atoms and aromatic diversity into complex structures.

Application

• Pharmaceutical Intermediate: A versatile synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or fluorinated liquid crystals.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up services for the fine chemical industry.

Basic Information

Product Name	2-Fluoro-6-m-Tolylpyridine
CAS No.	1245650-01-4
Molecular Formula	C₁₂H₁₀FN
Molecular Weight	187.21 g/mol
Synonyms	2-Fluoro-6-(3-methylphenyl)pyridine; 6-(3-Methylphenyl)-2-fluoropyridine; 2-Fluoro-6-(m-tolyl)pyridine; m-Tolyl-2-fluoropyridine; 3-Methylphenyl-2-fluoropyridine; 2-Fluoro-6-(3-tolyl)pyridine; 1245650-01-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-m-Tolylpyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are designed to meet the exacting requirements of research and industrial-scale synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	Contact for details
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.