Description

1,3-Difluoro-5-Butyl- Benzene is a high-purity fluorinated aromatic building block, essential for advanced organic synthesis. Its unique structure, featuring a butyl chain and strategically placed fluorine atoms, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the difluorobenzene moiety contributes to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where the butyl chain influences mesomorphic and electronic properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution, enabling the construction of complex, multi-substituted arenes.
• Fluorine Chemistry Research: Valuable substrate for studying structure-activity relationships (SAR) and developing new fluorination methodologies in academic and industrial R&D settings.

Basic Information

Product Name	1,3-Difluoro-5-Butyl- Benzene
CAS No.	1245649-46-0
Molecular Formula	C₁₀H₁₂F₂
Molecular Weight	170.20 g/mol
Synonyms	5-Butyl-1,3-difluorobenzene; 1,3-Difluoro-5-butylbenzene; 3-Butyl-1,5-difluorobenzene; Butyl-difluorobenzene; 1,3-Difluoro-5-n-butylbenzene; Difluorobutylbenzene; Benzene, 1,3-difluoro-5-butyl-
EINECS	Contact for details

Quality Control

Our 1,3-Difluoro-5-Butyl- Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.