Description

2-Fluoro-6-(4-Nitrophenyl)Pyridine is a high-purity, specialized heterocyclic building block featuring a fluoropyridine core linked to a nitrophenyl group. This compound is valued for its role as a key synthetic intermediate in advanced organic synthesis, where its unique substitution pattern enables precise molecular construction. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition or requiring fluorinated aromatic systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the nitrophenyl and fluoropyridine motifs can contribute to biological activity.
• Material Science: Acts as a building block for creating specialized ligands, organic semiconductors, or photoactive materials in OLED and electronic applications.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tags for studying biological processes and enzyme mechanisms.
• Cross-Coupling Reactions: The halogen and nitro functional groups make it a versatile substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for scaling up novel synthetic routes in process chemistry.

Basic Information

Product Name	2-Fluoro-6-(4-Nitrophenyl)Pyridine
CAS No.	1245648-41-2
Molecular Formula	C11H7FN2O2
Molecular Weight	218.19 g/mol
Synonyms	6-(4-Nitrophenyl)-2-fluoropyridine; 2-Fluoro-6-(p-nitrophenyl)pyridine; 4-(2-Fluoropyridin-6-yl)nitrobenzene; 2-Fluoro-6-(4-nitrophenyl)pyridine; Pyridine, 2-fluoro-6-(4-nitrophenyl)-; (4-Nitrophenyl)-2-fluoropyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(4-Nitrophenyl)Pyridine is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, supported by comprehensive analytical characterization including HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.