Description

4-(6-Fluoropyridin-2-Yl)Benzonitrile is a high-purity fluorinated aromatic nitrile building block. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients. The specific molecular architecture, combining a fluoropyridine with a benzonitrile moiety, offers versatile reactivity for constructing advanced heterocyclic systems.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the fluoropyridine unit can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a core structure for creating fluorescent tags or molecular probes for biological imaging and diagnostic applications.

Basic Information

Item	Details
Product Name	4-(6-Fluoropyridin-2-Yl)Benzonitrile
CAS No.	1245646-03-0
Molecular Formula	C₁₂H₇FN₂
Molecular Weight	198.20 g/mol
Synonyms	2-(4-Cyanophenyl)-6-fluoropyridine; 6-Fluoro-2-(4-cyanophenyl)pyridine; 4-(6-Fluoro-2-pyridinyl)benzonitrile; 4-(6-Fluoropyridin-2-yl)benzonitrile; 1245646-03-0; 4-(6-Fluoro-2-pyridyl)benzonitrile; 2-(4-Cyanophenyl)-6-fluoro-pyridine
EINECS	Contact for details

Quality Control

Our 4-(6-Fluoropyridin-2-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.