Description

1-(4-(6-Fluoropyridin-2-Yl)Phenyl)Ethanone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a fluoropyridine moiety with an acetophenone group, enabling precise structural modifications for developing novel compounds. This intermediate is primarily needed by R&D and process development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme function and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	1-(4-(6-Fluoropyridin-2-Yl)Phenyl)Ethanone
CAS No.	1245645-95-7
Molecular Formula	C13H10FNO
Molecular Weight	215.22 g/mol
Synonyms	2'-Fluoro-4-acetylbiphenyl-2-carbonitrile; 1-[4-(6-Fluoropyridin-2-yl)phenyl]ethan-1-one; 4-(6-Fluoro-2-pyridinyl)acetophenone; 6-Fluoro-2-(4-acetylphenyl)pyridine; 2-(4-Acetylphenyl)-6-fluoropyridine; 4-Acetyl-2'-fluorobiphenyl-2-carbonitrile; 1-(4-(6-Fluoropyridin-2-yl)phenyl)ethanone
EINECS	Contact for details

Quality Control

Our production of 1-(4-(6-Fluoropyridin-2-Yl)Phenyl)Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.