Description

8-Fluoro-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a fluorine atom with a fused triazolopyridine scaffold, making it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor programs and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Serves as a critical building block for synthesizing new generations of herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Precursor: Used in the development of advanced organic electronic materials, such as ligands for OLEDs and other fluorinated functional materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	8-Fluoro-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine
CAS No.	1245644-74-9
Molecular Formula	C6H4FN5
Molecular Weight	165.13 g/mol
Synonyms	8-Fluoro-[1,2,4]triazolo[1,5-a]pyridin-2-amine; 8-Fluoro-1,2,4-triazolo[1,5-a]pyridin-2-amine; 1245644-74-9; 8-Fluoro-1,2,4-triazolo[1,5-a]pyridin-2-ylamine; 2-Amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridine; 8-Fluoro-2-amino-[1,2,4]triazolo[1,5-a]pyridine
EINECS	Contact for details

Quality Control

Our 8-Fluoro-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting the specifications and results. Our quality commitment supports your R&D and scale-up processes with reliable, traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.