Description

4-Hydroxy-2-Trifluoromethylbenzaldehyde is a versatile aromatic aldehyde derivative characterized by the presence of both a phenolic hydroxyl group and a trifluoromethyl substituent. This unique molecular structure makes it a valuable high-purity building block for advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Active Ingredient Precursor: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Synthesis: Employed in the production of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing and aromatic properties.
• Chemical Research & Development: A fundamental building block in academic and industrial R&D for exploring new chemical reactions and synthesizing complex organic molecules.

Basic Information

Product Name	4-Hydroxy-2-Trifluoromethylbenzaldehyde
CAS No.	1243395-68-7
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	2-(Trifluoromethyl)-4-hydroxybenzaldehyde; 4-Hydroxy-2-(trifluoromethyl)benzaldehyde; 2-Trifluoromethyl-4-hydroxybenzaldehyde; 4-Hydroxy-α,α,α-trifluoro-o-tolualdehyde; 4-Hydroxy-2-trifluoromethylbenzenecarboxaldehyde; 2-Trifluoromethyl-4-hydroxybenzenecarboxaldehyde; 4-Hydroxy-2-(trifluoromethyl)benzenecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxy-2-Trifluoromethylbenzaldehyde is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development and commercial projects requiring material produced under GMP-like conditions for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.