Description

5-Chloro-4-Fluoro-2-Methylbenzene-1-Sulfonyl Chloride (Wx192221) is a high-purity, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual reactive sites, enabling the precise introduction of the sulfonyl moiety into complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs), including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the production of specialty polymers, dyes, and liquid crystals where sulfonyl groups modify material properties.
• Chemical Research: Versatile reagent for medicinal chemistry and process chemistry, facilitating structure-activity relationship (SAR) studies and route scouting.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Item	Details
Product Name	5-Chloro-4-Fluoro-2-Methylbenzene-1-Sulfonyl Chloride (Wx192221)
CAS No.	1242339-40-7
Molecular Formula	C7H5Cl2FO2S
Molecular Weight	247.08 g/mol
Synonyms	5-Chloro-4-fluoro-2-methylbenzenesulfonyl chloride; 2-Methyl-5-chloro-4-fluorobenzenesulfonyl chloride; 1-Chlorosulfonyl-5-chloro-4-fluoro-2-methylbenzene; WX-192221; Wx192221; 1242339-40-7; 5-Chloro-4-fluoro-o-toluenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-4-Fluoro-2-Methylbenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.