Description

Soluble Epoxide Hydrolase Inhibitor CAS NO 1241826-88-9 is a potent and selective small-molecule compound designed to inhibit the soluble epoxide hydrolase (sEH) enzyme. This inhibition is crucial for modulating the epoxyeicosatrienoic acid (EET) signaling pathway, which plays a significant role in regulating inflammation, vascular function, and pain. It is an essential research tool for pharmaceutical R&D, academic institutions, and biotechnology companies focused on developing novel therapeutics for cardiovascular diseases, neuropathic pain, diabetes, and other inflammatory conditions.

Application

• Pharmacological Research: A key reference standard and active compound for studying the sEH enzyme's role in disease models.
• Drug Discovery & Development: Used as a lead compound or intermediate in the synthesis of novel anti-inflammatory and analgesic agents.
• Biochemical Assays: Employed in high-throughput screening (HTS) and in vitro enzymatic assays to evaluate sEH inhibition potency.
• Preclinical Studies: Utilized in animal models to investigate the therapeutic potential of sEH inhibition for hypertension, renal disease, and metabolic syndrome.
• Mechanism of Action Studies: Essential for elucidating the biological pathways involving epoxy fatty acids and their impact on cellular function.

Basic Information

Product Name	Soluble Epoxide Hydrolase Inhibitor
CAS No.	1241826-88-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	sEH Inhibitor; 1-(1-Methanesulfonyl-piperidin-4-yl)-3-(4-trifluoromethoxy-phenyl)-urea (common structural analog class); Soluble Epoxide Hydrolase (sEH) Antagonist; Epoxide Hydrolase Inhibitor; EET Pathway Modulator; Anti-inflammatory Research Compound
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing batch-specific results for assay, purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0%
Water Content	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.