Description

3-Fluoro-5-(2-Methylpiperidin-1-Ylsulfonyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl piperidine-pyridine hybrid structure. This compound is of significant commercial value for its role in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorine atom and sulfonamide group, which can modulate potency, selectivity, and metabolic stability.
• Agrochemical Development: Serves as a precursor in the creation of new active ingredients for crop protection products, leveraging its heterocyclic scaffold.
• Chemical Biology Probe Synthesis: Utilized for designing and synthesizing molecular probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specialized intermediate.

Basic Information

Product Name	3-Fluoro-5-(2-Methylpiperidin-1-Ylsulfonyl)Pyridine
CAS No.	1241234-75-2
Molecular Formula	C11H15FN2O2S
Molecular Weight	258.31 g/mol
Synonyms	3-Fluoro-5-[(2-methyl-1-piperidinyl)sulfonyl]pyridine; 5-[(2-Methylpiperidin-1-yl)sulfonyl]-3-fluoropyridine; 1-(5-Fluoropyridin-3-yl)sulfonyl-2-methylpiperidine; 3-Fluoro-5-(2-methylpiperidine-1-sulfonyl)pyridine; 1241234-75-2
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(2-Methylpiperidin-1-Ylsulfonyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP development and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.