Description

2-Fluoropyrimidine-5-Carbaldehyde is a high-purity fluorinated pyrimidine building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, where the aldehyde group serves as a versatile handle for derivatization and the fluorinated pyrimidine ring is a key pharmacophore. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals. Its precise structure enables the creation of targeted molecular libraries for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs and other active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Research: Used as a key building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to synthesize fluorescent tags and molecular probes for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Fluoropyrimidine-5-Carbaldehyde
CAS No.	1240041-64-8
Molecular Formula	C5H3FN2O
Molecular Weight	126.09 g/mol
Synonyms	5-Formyl-2-fluoropyrimidine; 2-Fluoro-5-pyrimidinecarboxaldehyde; 2-Fluoropyrimidine-5-carboxaldehyde; Pyrimidine-5-carboxaldehyde, 2-fluoro-; 1240041-64-8; 2-Fluoropyrimidine-5-aldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoropyrimidine-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.