Description

5-Fluoro-6-Hydroxypicolinonitrile is a versatile and high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a nitrile and a hydroxyl group on a fluorinated pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Advanced Material Development: Building block for specialty polymers and electronic materials where fluorinated aromatics are required.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in multi-step custom synthesis projects for clients.

Basic Information

Product Name	5-Fluoro-6-Hydroxypicolinonitrile
CAS No.	1239510-82-7
Molecular Formula	C6H3FN2O
Molecular Weight	138.10 g/mol
Synonyms	6-Hydroxy-5-fluoropicolinonitrile; 5-Fluoro-6-hydroxypyridine-2-carbonitrile; 2-Cyano-5-fluoro-6-hydroxypyridine; 5-Fluoro-6-hydroxy-2-pyridinecarbonitrile; 5-Fluoro-6-oxo-1,6-dihydropyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-6-Hydroxypicolinonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.