Description

5-Fluoropyridine-2-Carbonitrile 1-Oxide is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals due to its unique fluorinated pyridine N-oxide structure. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a biochemical tool.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up services.

Basic Information

Product Name	5-Fluoropyridine-2-Carbonitrile 1-Oxide
CAS No.	1239510-81-6
Molecular Formula	C6H3FN2O
Molecular Weight	138.10 g/mol
Synonyms	2-Cyano-5-fluoropyridine 1-oxide; 5-Fluoro-2-cyanopyridine N-oxide; 5-Fluoropicolinonitrile 1-oxide; 5-Fluoro-2-pyridinecarbonitrile 1-oxide; 2-Pyridinecarbonitrile, 5-fluoro-, 1-oxide; 5-Fluoropyridine-2-carbonitrile N-oxide
EINECS	Contact for details

Quality Control

Our 5-Fluoropyridine-2-Carbonitrile 1-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.