Description

3-Bromo-2-Fluoro-5-(Trifluoromethyl)Benzaldehyde is a high-value, multi-functional aromatic aldehyde building block characterized by its unique halogen and trifluoromethyl substitution pattern. This compound is essential for medicinal chemistry and advanced materials research, where its structure enables precise modulation of electronic properties, lipophilicity, and metabolic stability in target molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Functional Material Research: Employed in the synthesis of ligands for catalysis and monomers for specialty polymers with tailored properties.

Basic Information

Product Name	3-Bromo-2-Fluoro-5-(Trifluoromethyl)Benzaldehyde
CAS No.	1236538-66-1
Molecular Formula	C8H3BrF4O
Molecular Weight	271.01 g/mol
Synonyms	3-Bromo-2-fluoro-5-(trifluoromethyl)benzaldehyde; 2-Fluoro-3-bromo-5-(trifluoromethyl)benzaldehyde; 5-(Trifluoromethyl)-3-bromo-2-fluorobenzaldehyde; Benzaldehyde, 3-bromo-2-fluoro-5-(trifluoromethyl)-; 1236538-66-1
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-2-Fluoro-5-(Trifluoromethyl)Benzaldehyde adheres to strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our facilities operate under cGMP principles where applicable, ensuring traceability and reliability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.