Description

2-Fluoro-5-Formylbenzamide is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a formyl and an amide group on a fluorinated benzene ring, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, CNS agents, and anti-inflammatory compounds.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced activity and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic units.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.
• Academic and R&D Laboratories: Used in fundamental research exploring new organic reactions and the properties of fluorinated compounds.

Basic Information

Product Name	2-Fluoro-5-Formylbenzamide
CAS No.	1236289-88-5
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	5-Formyl-2-fluorobenzamide; 2-Fluoro-5-carbamoylbenzaldehyde; Benzamide, 2-fluoro-5-formyl-; 2-Fluorobenzamide-5-carboxaldehyde; 2-Fluoro-5-formyl-benzoic acid amide; 5-Aminocarbonyl-2-fluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Formylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.