Description

(+)-trans-C75 CAS NO 1234694-20-2 is a high-purity, stereochemically defined synthetic compound of significant interest in biochemical and pharmacological research. Its primary value lies in its role as a potent and selective inhibitor of fatty acid synthase (FAS), a key enzyme in the *de novo* lipogenesis pathway. This makes it a critical research tool for scientists investigating metabolic disorders, cancer biology, and appetite regulation. Researchers in pharmaceutical development, academic institutions, and contract research organizations (CROs) require this specific enantiomer for precise mechanistic studies and target validation.

Application

• Biochemical Research: Used as a specific tool compound to inhibit fatty acid synthase (FAS) and study lipid metabolism pathways in cell-based assays.
• Oncology Research: Investigated for its potential anti-cancer properties, as many tumor cells exhibit upregulated FAS activity for membrane synthesis and proliferation.
• Metabolic Disease Studies: Applied in research models for obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD) to understand the role of *de novo* lipogenesis.
• Neuroscience & Appetite Regulation: Utilized in studies exploring the central nervous system's control of food intake, as C75 administration affects hypothalamic signaling.
• Pharmacology & Drug Discovery: Serves as a reference standard and lead compound in the development of novel FAS inhibitors for therapeutic applications.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in biochemistry and molecular biology.

Basic Information

Product Name	(+)-trans-C75
CAS No.	1234694-20-2
Molecular Formula	C19H31NO2
Molecular Weight	305.46 g/mol
Synonyms	(+)-trans-4-Methylene-5-oxo-tetradec-2-enedioic acid 2-hydroxy-2-methylpropylamide; (2E,4R)-4-Methylene-5-oxo-2-tetradecenedioic acid 2-hydroxy-2-methylpropylamide; trans-(+)-C75; (R,E)-C75; FAS Inhibitor C75 (enantiomer); Fatty Acid Synthase Inhibitor (+)-C75; C75 (trans, +)
EINECS	Contact for details

Quality Control

Our (+)-trans-C75 is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting all specifications and test results is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The compound is moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.