Description

(5-Bromo-3-Fluoropyridin-2-Yl)Methanamine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated and amine-functionalized motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the bromo-fluoro-pyridine scaffold provides specific bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring precise halogen and amine functionalization on a pyridine ring.

Basic Information

Product Name	(5-Bromo-3-Fluoropyridin-2-Yl)Methanamine
CAS No.	1234616-19-3
Molecular Formula	C6H6BrFN2
Molecular Weight	205.03 g/mol
Synonyms	2-(Aminomethyl)-5-bromo-3-fluoropyridine; 1-(5-Bromo-3-fluoropyridin-2-yl)methanamine; (5-Bromo-3-fluoro-2-pyridinyl)methanamine; 5-Bromo-3-fluoro-2-pyridinemethanamine; 2-Aminomethyl-5-bromo-3-fluoropyridine; 5-Bromo-3-fluoro-pyridin-2-ylmethylamine
EINECS	Contact for details

Quality Control

Our (5-Bromo-3-Fluoropyridin-2-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.