Description

2-Ethynyl-4-Fluoro-1-Methylbenzene is a specialized aromatic building block featuring both an ethynyl and a fluoro substituent on a methylbenzene core. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, particularly in the development of targeted therapies and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating molecules with specific receptor binding profiles.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems used in fine chemical synthesis.
• Fluorine Chemistry Studies: Acts as a model compound in academic and industrial research focused on the reactivity of fluorinated aromatic alkynes.

Basic Information

Product Name	2-Ethynyl-4-Fluoro-1-Methylbenzene
CAS No.	1233512-88-3
Molecular Formula	C9H7F
Molecular Weight	134.15 g/mol
Synonyms	4-Fluoro-2-ethynyl-1-methylbenzene; 1-Fluoro-3-ethynyl-4-methylbenzene; 2-Ethynyl-4-fluorotoluene; 4-Methyl-3-ethynylfluorobenzene; 3-Ethynyl-4-fluorotoluene; 2-Fluoro-5-methylphenylacetylene
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-4-Fluoro-1-Methylbenzene is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.