Description

6-Fluoro-5-Amino-3-Pyridinecarbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines an electron-withdrawing cyano group and a fluorine substituent with an aromatic amine, enabling precise modifications in complex molecular frameworks. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, dyes, and functional polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a building block for fluorescent tags or molecular probes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploration of new heterocyclic chemistry.

Basic Information

Product Name	6-Fluoro-5-Amino-3-Pyridinecarbonitrile
CAS No.	1232432-79-9
Molecular Formula	C6H4FN3
Molecular Weight	137.12 g/mol
Synonyms	5-Amino-6-fluoropyridine-3-carbonitrile; 3-Cyano-5-amino-6-fluoropyridine; 6-Fluoro-5-aminonicotinonitrile; 5-Amino-6-fluoro-3-cyanopyridine; 6-Fluoro-5-aminonicotinamide nitrile precursor; 2-Fluoro-3-amino-5-cyanopyridine (isomer reference); 5-Amino-6-fluoronicotinonitrile
EINECS	Contact for details

Quality Control

Our 6-Fluoro-5-Amino-3-Pyridinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.