Description

5-Bromo-2-Fluoropyridin-4-Amine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which enables precise molecular modifications essential for developing novel compounds. This intermediate is primarily sought after by pharmaceutical and agrochemical R&D teams for the creation of active ingredients, as well as by specialty chemical manufacturers producing functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Functional Material Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Utilized as a building block for designing molecular probes and tags used in bio-conjugation and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Bromo-2-Fluoropyridin-4-Amine
CAS No.	1232430-97-5
Molecular Formula	C5H4BrFN2
Molecular Weight	191.00 g/mol
Synonyms	4-Amino-5-bromo-2-fluoropyridine; 2-Fluoro-5-bromopyridin-4-amine; 5-Bromo-2-fluoro-4-pyridinamine; 5-Bromo-2-fluoropyridin-4-ylamine; 4-Pyridinamine, 5-bromo-2-fluoro-; 2-Fluoro-5-bromo-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoropyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates, including those under development for regulatory submission.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.