Description

Tamsulosin-D4 CAS NO 1231943-97-7 is a deuterium-labeled analog of Tamsulosin, a selective α-1A adrenergic receptor antagonist. This stable isotope-labeled compound is an essential internal standard for the precise quantification of Tamsulosin in complex biological matrices using advanced analytical techniques like LC-MS/MS. It is a critical tool for pharmaceutical research and development, clinical laboratories, and forensic toxicology. Professionals in these fields rely on it to ensure the accuracy, reliability, and regulatory compliance of their pharmacokinetic and bioanalytical studies.

Application

• Internal Standard for Bioanalysis: Primary use as a quantitative reference standard in Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) for Tamsulosin in plasma, serum, and urine.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Drug Development and Quality Control: Supports method development, validation, and routine quality control testing in pharmaceutical manufacturing.
• Clinical Research and Therapeutic Drug Monitoring (TDM): Facilitates precise measurement of drug concentrations in patients to optimize dosing regimens and ensure therapeutic efficacy.
• Forensic and Doping Control Analysis: Used in confirmatory testing for the presence of Tamsulosin in forensic toxicology and anti-doping laboratories.
• Metabolite Identification and Profiling: Aids in the structural elucidation and quantification of Tamsulosin metabolites.

Basic Information

Item	Detail
Product Name	Tamsulosin-D4
CAS No.	1231943-97-7
Molecular Formula	C20H24D4N2O5S
Molecular Weight	408.53 g/mol (approx.)
Synonyms	5-[(2R)-2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide-d4; Tamsulosin-d4; Tamsulosin (phenyl-d4); Deuterated Tamsulosin; Tamsulosin Internal Standard; Tamsulosin-d4 for LC-MS; (R)-Tamsulosin-d4; FLOMAX-d4
EINECS	Contact for details

Quality Control

Every batch of Tamsulosin-D4 is manufactured and analyzed under strict quality systems. We ensure compliance with the highest standards for stable isotope-labeled compounds, with a focus on isotopic purity and chemical identity. Comprehensive testing includes identification by spectroscopic methods (NMR, IR), assay by HPLC, determination of isotopic enrichment by MS, and control of related substances. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.