Description

5-Fluoro-2-Pivalamidonicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific nicotinic acid derivative structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation small molecule drugs and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides due to its fluorinated heterocyclic structure.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex pivalamide and nicotinic acid derivatives in organic chemistry.
• Biochemical Research: Employed in biochemical studies as a tool compound to investigate biological processes and receptor interactions.
• Material Science: Potential use in the development of specialty chemicals and functional materials requiring fluorinated components.

Basic Information

Item	Detail
Product Name	5-Fluoro-2-Pivalamidonicotinic Acid
CAS No.	1228666-46-3
Molecular Formula	C11H13FN2O3
Molecular Weight	240.23 g/mol
Synonyms	5-Fluoro-2-(2,2-dimethylpropanamido)nicotinic acid; 2-Pivalamido-5-fluoronicotinic acid; 5-Fluoro-2-pivalamidopyridine-3-carboxylic acid; 1228666-46-3; 5-Fluoro-2-(pivalamido)nicotinic acid; 3-Carboxy-5-fluoro-2-pivalamidopyridine; 5-Fluoro-2-(2,2-dimethylpropionamido)nicotinic Acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Pivalamidonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.