Description

3-(2-Amino-5-Fluoropyridin-3-Yl)Propan-1-Ol is a high-purity fluorinated pyridine derivative, serving as a critical building block in modern organic synthesis. Its molecular structure, featuring both an amino group and a fluorinated aromatic ring, makes it an invaluable intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A versatile reagent for academic and industrial research in medicinal chemistry and material science.
• Fluorine-Containing Compound Library: Essential for building diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Item	Details
Product Name	3-(2-Amino-5-Fluoropyridin-3-Yl)Propan-1-Ol
CAS No.	1228666-36-1
Molecular Formula	C8H11FN2O
Molecular Weight	170.18 g/mol
Synonyms	3-(2-Amino-5-fluoropyridin-3-yl)propan-1-ol; 3-(2-Amino-5-fluoro-3-pyridinyl)-1-propanol; 2-Amino-5-fluoro-3-(3-hydroxypropyl)pyridine; 5-Fluoro-3-(3-hydroxypropyl)pyridin-2-amine; 1228666-36-1; 3-(2-Amino-5-fluoropyridin-3-yl)propanol
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Amino-5-Fluoropyridin-3-Yl)Propan-1-Ol is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including HPLC, NMR, and MS data, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each shipment, detailing specifications such as assay, impurity profile, and residual solvents. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.