Description

Methyl 2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinate is a high-value fluorinated nicotinate derivative and a key synthetic intermediate in modern organic chemistry. Its molecular structure, featuring a fluorine atom and a pyrrolidine-substituted pyridine ring, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical development teams engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting neurological disorders and other therapeutic areas where fluorinated heterocycles are advantageous.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing complex fluorinated pyridine derivatives in academic and industrial R&D laboratories.
• Ligand and Catalyst Development: The nitrogen-rich structure makes it a candidate for developing novel ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Investigated for the creation of specialty polymers and advanced organic electronic materials due to its unique electronic properties.

Basic Information

Product Name	Methyl 2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinate
CAS No.	1228666-19-0
Molecular Formula	C11H13FN2O2
Molecular Weight	224.23 g/mol
Synonyms	2-Fluoro-6-(pyrrolidin-1-yl)nicotinic acid methyl ester; Methyl 2-fluoro-6-(1-pyrrolidinyl)-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid, 2-fluoro-6-(1-pyrrolidinyl)-, methyl ester; 1228666-19-0; 2-Fluoro-6-pyrrolidin-1-yl-nicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.