Description

2-Fluoro-6-(Pyrrolidin-1-Yl)Isonicotinonitrile is a high-value, fluorinated heterocyclic building block designed for advanced chemical synthesis. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, including central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization due to its fluoropyridine and nitrile functionalities.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-Fluoro-6-(Pyrrolidin-1-Yl)Isonicotinonitrile
CAS No.	1228666-18-9
Molecular Formula	C10H10FN3
Molecular Weight	191.21 g/mol
Synonyms	2-Fluoro-6-(pyrrolidin-1-yl)isonicotinonitrile; 6-Fluoro-2-(pyrrolidin-1-yl)pyridine-4-carbonitrile; 4-Cyano-6-fluoro-2-(1-pyrrolidinyl)pyridine; 2-(Pyrrolidin-1-yl)-6-fluoropyridine-4-carbonitrile; 1228666-18-9; 2-Fluoro-6-(1-pyrrolidinyl)-4-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(Pyrrolidin-1-Yl)Isonicotinonitrile is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.